石旭生 | Shih, Hsu Sheng
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曾維昌|Tseng, Wei-chang
🎓 副教授兼醫學檢驗生物技術系主任
👨🎓 高雄醫學大學醫學研究所理學博士
📞 07-7811151 轉6210 或 5315
📧 sc120@fy.edu.tw
📖 學術專長
重金屬微量元素分析、抗氧化與過氧化研究、輸血醫學檢驗、電腦軟體應用
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學歷
- 高雄醫學大學醫學研究所理學博士(2003)
- 高雄醫學大學醫學研究所碩士(1995)
- 高雄醫學大學醫學技術學系學士(1993)
經歷
- 台南市物理治療師公會 理事長
- 中華民國物理治療師公會全國聯合會 理事
- 政府社會局輔具資源中心(西站)計畫主持人
- 台南市教育局申訴評議委員會委員
- 中華民國物理治療師公會全國聯合會 會員代表
- 台南市物理治療師公會 理事
- 台南市物理治療師公會 監事
- 台南縣立大愛診所 復健部 物理治療師
- 台南市無障礙福利之家 復健部 治療師
學術專長
- 重金屬微量元素分析
- 抗氧化與過氧化研究
- 輸血醫學檢驗
- 電腦軟體應用
專題/論文指導
- 104 學年度專題:Polymorphisms of the UDP-Glucuronosyl Transferase 1A7 Gene with Endometrial Cancer
- 107學年度專題: 利用線上微透析取樣及線上前濃縮配合火焰原子吸收光譜發展複雜基質樣品的金屬直測分析技術
- 106 學年度專題: 鎂和氧化壓力在第二型糖尿病的相關研究
- 105 學年度專題: 評估脂質過氧化的丙二醛成為糖尿性腎病變參考指標
- 104 學年度專題: 採血時間血品之各項指標探討
- 103 學年度專題: 利用血小板抗體篩檢與鑑定以解決血小板輸注無效
- 102 學年度專題: 物件清洗裝置之研發
- 101 學年度專題: 快速偵測脂質過氧化產物 MDA 之分析方法開發
證照
- 醫事檢驗師
期刊論文
- 2016,3:75-92.1.Tsao DA, Tseng WC, Chang HR*. RKIP Expression of Liver and Kidney After Arsenic Exposure. Environ. Toxicol. 2017 Mar;32(3):1079-1082.
- Tseng WC, Hsu KC, Shiea CS, Huang YL*. Recent trends in nanomaterial-based microanalytical systems for the speciation of trace elements: A critical review. Anal Chim Acta. 2015 Jul 16;884:1-18.
Hsu KC, Lee CF, Tseng WC, Chao YY, Huang YL*. Selective and eco-friendly method for determination of mercury(II) ions in aqueous samples using an on-line AuNPs-PDMS composite microfluidic device/ICP-MS system. Talanta. 2014 Oct; 128:408-13. - 李貞堅、劉全喜、陳俊憲、詹爾昌、曾維昌、施盛棟、朱紀實、陳祈宏、洪琪幃,南部某教學醫院 Carbapenam-resistant Acinetobacter baumannii 菌株(CRAB) 之抗藥盛行率。醫檢會報第 27 卷第 4 期第 224-228 頁。
- Wang YF, Shyu HW, Chang YC, Tseng WC, Huang YL, Lin KH, Chou MC, Liu HL, Chen CY*. Nickel (II)-induced cytotoxicity and apoptosis in human proximal tubule cells through a ROS- and mitochondria-mediated pathway. Toxicol. Appl. Pharmacol. 2012 March;259(2):177-186.
- Chang HR*, Tsao DA, Tseng WC. The expression of RKIP, RhoGDI, galectin, c‐Myc and p53 in gastrointestinal system of Cr(VI)‐exposed rats. J. Appl. Toxicol., 2011 31:730-740.
- Chang HR*, Tsao DA, Tseng WC. Hexavalent chromium inhibited the expression of RKIP of heart in vivo and in vitro. Toxicol. in vitro, 2011 Feb;25(1):1–6.
- Tseng WC*. A novel suggestion on clinical determination of metals in whole blood by simultaneous atomic absorption spectrometry. J. Biomed. Lab. Sci., 2009 Oct; 21(3), 77–81.
- Tsay TS, Huang YL, Tseng WC*. Simultaneous determination of aluminum, cadmium and lead in whole blood by simultaneous atomic absorption spectrometry with oxygen charring.J. Chin. Chem. Soc., 2009 Feb; 56(1), 135–141.曾維昌*. 可怕的重金屬. 輔英醫訊, 2008; 59, 9–9.
- Chen CY, Liu TZ, Tseng WC, Lu FJ, Hung RP, Chen CH, Chen CH. (-)-Anonaine induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa)cells. Food & Chem. Toxicol., 2008 Aug; 46(8), 2694–2702.
- Chen CY, Liu TZ, Liu YW, Tseng WC, Liu RH, Lu FJ, Lin YS, Kuo SH, Chen CH. 6-shogaol (alkanone from ginger) induces apoptotic cell death of human hepatoma p53 mutant Mahlavu subline via an oxidative stress-mediated caspase-dependent mechanism. J.Agric. Food Chem., 2007 Feb; 55(3):948–954.
- Tseng WC, Chen PH, Tsay TS, Chen BH, Huang YL. Continuous multi-element (Cu, Mn,Ni, Se) monitoring in saline and cell suspension using on-line microdialysis coupled with simultaneous electrothermal atomic absorption spectrometry. Anal. Chim. Acta, 2006 Aug; 576(1):2–8.
- Lin SJ, Lee CF, Tseng WC, Huang YL. Real-time dynamic monitoring of non-protein-bound copper in the blood. Biol. Trace Elem. Res. 2006 summer; 111(1-3):255–263.
- Chang HR, Cheng TL, Liu TZ, Hu HS, Hsu LS, Tseng WC, Chen CH, Tsao DA. Genetic and cellular characterizations of human TCF4 with microsatellite instability in colon cancer and leukemia cell lines. Cancer Lett. 2006 Feb 20;233(1):165-71.
- Chang HR, Cheng TL, Liu TZ, Hu HS, Hsu LS, Tseng WC, Chen CH, Tsao DA. Genetic and cellular characterizations of human TCF4 with microsatellite instability in colon cancer and leukemia cell lines. Cancer Lett., 2006 Feb; 233(1):165–171.
- Tseng WC, Cheng GW, Lee CF, Wu HL, Huang YL. On-line coupling of microdialysis sampling with high performance liquid chromatography and hydride generation atomic absorption spectrometry for continuous in vivo monitoring of arsenic species in the blood of living rabbits. Anal. Chim. Acta, 2005 July; 543(1-2):38–45.
- Tseng WC, Sun YC, Lee CF, Chen BH, Yang MH, Huang YL. On-line microdialysis sampling coupled with flame atomic absorption spectrometry for continuous in vivo monitoring of diffusible magnesium in the blood of living animals. Talanta, 2005 April; 66(3):740–745.
- Tseng WC, Sun YC, Lee CF, Yang MH, Huang YL. Continuous in vivo monitoring of blood diffusible calcium using microdialysis sampling coupled on-line with flame atomic absorption spectrometry. Anal. Sci., 2005 Mar; 21(3):225–229.
- Lin PC, Tseng WC, Hsiech CM, Shih TS, Huang YL*. Speciation of urinary arsenic using glutathione as pre-reductant by HPLC and flow-injection HGAAS. Journal of Occupational Safety and Health, 2005, Mar; 13(1): 46–57.
- Sun YC, Lee YS, Shiah TL, Lee PL, Tseng WC, Yang MH. Comparative study on conventional and low-flow nebulizers for arsenic speciation by means of micro liquid chromatography with inductively coupled plasma mass spectrometry. J. Chromatogr. A,2003, Jul; 1005(1-2):207–213.
- Sheu JY, Chen PH, Tseng WC, Chen CY, Tsai LY, Huang YL. Spectrophotometric determination of thiobarbituric acid-reactive substance in human hair. Anal. Sci., 2003 Jun;19(6):957–960.
- Sheu JY, Ku HP, Tseng WC, Chen MT, Tsai LY, Huang YL. Determination of the thiobarbituric acid adduct of malondialdehyde using on-line microdialysis coupled with high performance liquid chromatography. Anal. Sci., 2003 Apr; 19(4):621–624.
- Tseng WC, Sun YC, Yang MH, Chen TP, Lin TH, Huang YL. On-line microdialysis sampling coupled with flow injection electrothermal atomic absorption spectrometry for in vivo monitoring of extracellular manganese in brains of living rats. J. Anal. At. Spectrom.,2003 Jan; 18(1):38–43.
- Tseng WC, Yang MH, Chen TP, Huang YL. Automated, continuous, and dynamic speciation of urinary arsenic in the bladder of living organisms using microdialysis sampling coupled on-line with high performance liquid chromatography and hydride generation atomic absorption spectrometry. Analyst, 2002 Apr ; 127(4):560–564.
- Huang YL, Tseng WC, Lin TH. In vitro effects of metal ions (Fe , Mn , Pb ) on sperm motility and lipid peroxidation in human semen. J. Toxicol. Environ. Health, 2001; 62 (4):259–267.
- Huang YL, Tseng WC, Cheng SY, Lin TH. Trace elements and lipid peroxidation in human seminal plasma. Biol. Trace Elem. Res., 2000; 76(3):207–215. 曾維昌、黃友利、謝俊明、石東生、林德賢. 勞工生物檢體汞物種偵測分析方法研究。勞工安全衛生研究季刊, 2000; 8 (1):17–31.
- Yiin SJ, Chern CL, Sheu JY, Tseng WC, Lin TH. Cadmium-induced renal lipid peroxidation in rats and protection by selenium. J. Toxicol. Environ. Health, 1999; 57(6):403–413.
- Lin TH, Tseng WC, Cheng SY. Direct determination of selenium in human blood plasma and seminal plasma by graphite furnace atomic absorption spectrophotometry and clinical application. Biol. Trace Elem. Res., 1998; 64(1-3):133–149.
- Lin TH, Huang YL, Tseng WC. Arsenic and lipid-peroxidation in patients with blackfoot disease. Bull. Environ. Contam. Toxicol., 1995; 54(4):488–493.
研究計畫
- 利用短管柱且自動進樣之超高效能液相層析法發展快速偵測血清或尿液中氧化壓力生物指標的檢驗方法VHLC-107011
- 利用線上微透析取樣及線上前濃縮配合火焰原子吸收光譜發展複雜基質樣品的金屬直測分析技術MOST 107-2637-M-242-001 -
- 鎂和氧化壓力在第二型糖尿病的相關研究VHLC-107008
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